Frasier: The set designers spent nearly half a million dollars on Frasier Crane's deluxe apartment, with $15,000 dedicated to a replica of Coco Chanel's couch.
Boy Meets World: The non-adult cast members, including Ben Savage and Danielle Fishel, learned together in real life, using a classroom near the set for studying.
Home Improvement: Richard Karn, who played Al Borland, got the role after being sent to traffic school for a moving violation and learning about the show from an agent in his class.
Twin Peaks: Co-creator David Lynch liked working with Sheryl Lee so much that he created another role (Maddy Ferguson) to keep her in the show.
NYPD Blue: While the show featured some real New York footage, most of it was shot on a set originally built for the 1969 film Hello, Dolly! in Los Angeles.
All That: Emma Stone, now a comedy star, auditioned for the children's sketch show at 12 years old but didn't get cast.
Wings: John Ritter's guest appearance on the sitcom led to his eventual marriage to co-star Amy Yasbeck, who played his ex-wife on the show.
Dawson's Creek: The show initially wanted to use Alanis Morrisette's "Hand in My Pocket" as the theme song but couldn't secure the rights, leading to Paula Cole's "I Don't Want to Wait" becoming the hit theme.